When these materials are not disposed of or treated properly, they can cause serious health hazards. Direct contact with these harmful materials or exposure to toxic fumes can lead to health problems such as skin irritation, respiratory issues, and even cancer. In addition, recycling activities such as open burning or dismantling of electrical equipment carry an increased risk. For example lead exposure during handling lead-acid batteries can lead to acute lead poisoning. Lead affects the kidneys, the nervous system, the cardiovascular, reproductive and immune system, and causes permanent developmental impairments to children. Severe lead poisoning can have lethal effects.